Hulk angry because bad guy keeps punching wizard-boy!

Swap Lockjaw for the new Hulk ally with Defender trait (+1 ATK after the villain attacks you).

Use Cameo to put Wiccan into you deck.

This is a modified version of Infinite combo deck by SDx (https://marvelcdb.com/decklist/view/61571/spider-ham-cartoonishly-cracked-otk-infinite-combo-1.0) not meant to win in a single turn, but rather boost Hulk enough to OTKO/2TKO the villain, even if they have the annoying 'cannot take damage this phase' effect.

Play your normal Spider-Ham game, until you have Hulk on board, Suit Up and Regroupin hand, plus enough resources/cartoon counters to fuel the whole thing up, flip up to AE and start the usual combo next turn.

Fish out Wiccan and Clarity of Purpose, play Regroup and Wiccan, get Petulant Pig and start sticking out the tongue on the villain while hiding behind the Young Avenger. This, for some reason, will make Hulk really angry. Repeat long enough so that the jolly green giant can make short work of the villain. You probably will draw Command Team at some point, which will make it faster if you don't care about growing Hulk too much.

Spend Cartoon Physics on overkill attacks if needed.